{"id":5211,"date":"2026-06-02T02:26:10","date_gmt":"2026-06-02T02:26:10","guid":{"rendered":"https:\/\/www.fintechpulse8.com\/?p=5211"},"modified":"2026-06-02T02:26:10","modified_gmt":"2026-06-02T02:26:10","slug":"equillium-inc-eq-discusses-mechanistic-insights-linking-ahr-signaling-and-mir-124-in-inflammatory-disease-transcript","status":"publish","type":"post","link":"https:\/\/www.fintechpulse8.com\/?p=5211","title":{"rendered":"Equillium, Inc. (EQ) Discusses Mechanistic Insights Linking AhR Signaling and miR-124 in Inflammatory Disease Transcript"},"content":{"rendered":"<p><\/p>\n<div>\n<header class=\"flex flex-col items-start justify-between\"\/>\n<div class=\"relative mb-18 flex items-start justify-between\" data-test-id=\"author-brief\">\n<div class=\"relative z-0 mr-18 flex\">\n<div class=\"flex shrink-0 items-center justify-center relative size-36 rounded-full\" data-test-id=\"user-pic-wrapper\"><img decoding=\"async\" alt=\"\" class=\"text-transparent flex w-full items-center justify-center overflow-hidden text-black-5 rounded-full h-full bg-black-5 dark:bg-black-30\" data-test-id=\"user-pic\" height=\"36\" loading=\"lazy\" src=\"https:\/\/seekingalpha.com\/images\/users_profile\/000\/101\/639\/big_pic.png?io=w72 2x\" width=\"36\"\/><\/div>\n<\/div>\n<p><button data-state-text=\"Following\" aria-label=\"Follow SA Transcripts\" class=\"ihjjQ py-8 px-18 ml-auto print:hidden relative inline-flex items-center justify-center select-none hover:no-underline transition-colors motion-reduce:transition-none border-black bg-black text-white hover:bg-black-70 disabled:border-transparent disabled:bg-black-20 dark:border-black-10 dark:bg-black-10 dark:text-black dark:hover:border-black-30 dark:hover:bg-black-30 dark:disabled:bg-black-30 min-h-36 border text-medium-b px-16 py-1 whitespace-nowrap break-words rounded-8 cursor-pointer\" data-test-id=\"follow-button\" type=\"button\"><span class=\"\"><span aria-hidden=\"true\" class=\"wMAFB relative flex justify-center\" data-state-placeholder=\"Following\"><span class=\"absolute\">Follow<\/span><\/span><\/span><\/button><\/div>\n<p><span class=\"block bg-black-10 opacity-30 dark:bg-black-35 w-full h-30 mb-16\" data-test-id=\"loader\"\/><\/p>\n<div class=\"mb-12\">\n<div aria-label=\"Audio player\" class=\"relative mb-8 mr-8\"><button id=\"sa-audio-player-play-button\" class=\"inline-flex items-center font-bold md:hidden relative inline-flex items-center justify-center select-none hover:no-underline transition-colors motion-reduce:transition-none border-black bg-black text-white hover:bg-black-70 disabled:border-transparent disabled:bg-black-20 dark:border-black-10 dark:bg-black-10 dark:text-black dark:hover:border-black-30 dark:hover:bg-black-30 dark:disabled:bg-black-30 min-h-36 border text-medium-b size-36 p-6 whitespace-nowrap break-words rounded-8 cursor-pointer shrink-0\" data-test-id=\"play-button\" type=\"button\"><span aria-hidden=\"true\" class=\"size-24 m-0 relative flex shrink-0 items-center justify-center [&amp;&gt;svg]:max-h-full [&amp;&gt;svg]:max-w-full [&amp;&gt;svg]:shrink-0 [&amp;&gt;svg]:grow [&amp;&gt;svg]:fill-current\"><span class=\"flex size-16 text-current\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewbox=\"0 0 16 16\" class=\"flex shrink-0 fill-current\" data-test-id=\"play-button-play-svg\"><path fill=\"currentColor\" d=\"M0 16V0l16 8z\"\/><\/svg><\/span><\/span><span class=\"sr-only\"><span class=\"font-bold b4Wu7\">Play Earnings Call<\/span><\/span><\/button><button id=\"sa-audio-player-play-button\" class=\"items-center font-bold hidden md:inline-flex relative inline-flex items-center justify-center select-none hover:no-underline transition-colors motion-reduce:transition-none border-black bg-black text-white hover:bg-black-70 disabled:border-transparent disabled:bg-black-20 dark:border-black-10 dark:bg-black-10 dark:text-black dark:hover:border-black-30 dark:hover:bg-black-30 dark:disabled:bg-black-30 min-h-36 border text-medium-b px-16 py-1 whitespace-nowrap break-words rounded-8 cursor-pointer\" data-test-id=\"play-button\" type=\"button\"><span aria-hidden=\"true\" class=\"size-24 mr-8 relative flex shrink-0 items-center justify-center [&amp;&gt;svg]:max-h-full [&amp;&gt;svg]:max-w-full [&amp;&gt;svg]:shrink-0 [&amp;&gt;svg]:grow [&amp;&gt;svg]:fill-current\"><span class=\"flex size-16 text-current\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewbox=\"0 0 16 16\" class=\"flex shrink-0 fill-current\" data-test-id=\"play-button-play-svg\"><path fill=\"currentColor\" d=\"M0 16V0l16 8z\"\/><\/svg><\/span><\/span><span class=\"\"><span class=\"font-bold b4Wu7\">Play Earnings Call<\/span><\/span><\/button><\/div>\n<\/div>\n<div>\n<div class=\"paywall-full-content R6FbO flex sa-text-content sa-media-content sa-table-content sa-content-helpers print:block mb-32\">\n<div class=\"w-0 grow print:w-auto\">\n<div>\n<div class=\"T2G6W\" data-test-id=\"content-container\">\n<div class=\"transcript-headline\">\n<p data-eci=\"true\">Equillium, Inc. (<span class=\"ticker-hover-wrapper\">EQ<\/span>) Discusses Mechanistic Insights Linking AhR Signaling and miR-124 in Inflammatory Disease May 27, 2026 11:00 AM EDT<\/p>\n<\/div>\n<div class=\"transcript-company-participants\">\n<p class=\"transcript-company-participants-title\"><strong>Company Participants<\/strong><\/p>\n<p><span>Stephen Connelly &#8211; Chief Scientific Officer &amp; President<\/span><\/p>\n<\/p><\/div>\n<div class=\"transcript-other-participants\">\n<p class=\"transcript-other-participants-title\"><strong>Conference Call Participants<\/strong><\/p>\n<p><span>Steven Seedhouse &#8211; Cantor Fitzgerald &amp; Co., Research Division<\/span><br \/><span>Thomas Smith &#8211; Leerink Partners LLC, Research Division<\/span><br \/><span>Alexander Thompson &#8211; Stifel, Nicolaus &amp; Company, Incorporated, Research Division<\/span><br \/><span>Jakob Hebert &#8211; Raymond James &amp; Associates, Inc., Research Division<\/span><br \/><span>Leland Gershell &#8211; Oppenheimer &amp; Co. Inc., Research Division<\/span><br \/><span>William Wood &#8211; B. Riley Securities, Inc., Research Division<\/span><br \/><span>Adam Walsh &#8211; ROTH Capital Partners, LLC, Research Division<\/span><\/p>\n<\/p><\/div>\n<div class=\"transcript-presentation\">\n<p class=\"transcript-presentation-title\"><strong>Presentation<\/strong><\/p>\n<div class=\"transcript-presentation-section\" seq=\"0\">\n<p class=\"transcript-presentation-section-title\"><span><strong>Operator<\/strong><\/span><\/p>\n<p>Good morning, and welcome to the Equillium Virtual Investor Event. [Operator Instructions] As a reminder, this call is being recorded, and a replay will be made available on the Equillium website following the conclusion of the event. <\/p>\n<p>I&#8217;d now like to turn the call over to your host, Stephen Connelly, Chief Scientific Officer at Equillium. Please go ahead.<\/p>\n<\/p><\/div>\n<div class=\"transcript-presentation-section\" seq=\"1\">\n<p class=\"transcript-presentation-section-title\"><span><strong>Stephen Connelly<\/strong><\/span><br \/><span><i>Chief Scientific Officer &amp; President<\/i><\/span><\/p>\n<p>Thanks, Tara, and good morning, everyone, and thanks for joining today&#8217;s webinar titled Insights to the Aryl Hydrocarbon Receptor and miR-124 Axis. <\/p>\n<p>Now before we start, it probably makes sense to give you a little bit of context on this work from the outset, both the Aryl Hydrocarbon Receptor and miR-124 are two distinct biological molecules. And indeed, therapeutic strategies modulating both of them have been shown to be effective in treating ulcerative colitis. However, data exists from cells, animals and humans that point to a more direct and functional relationship between these two molecules. And despite the biological and therapeutic relevance, the paradoxical relationship between these two has remained elusive and controversial. So understanding this relationship has critically important implications for both mechanistic interpretation and rational development of therapies targeting the AhR\/miR-124 Axis in inflammatory disease. <\/p>\n<p>So presented here<\/p>\n<\/p><\/div>\n<\/p><\/div>\n<\/div>\n<aside\/><\/div>\n<\/div>\n<\/div>\n<\/div>\n<footer class=\"border-t border-share-separator-thin py-18 sm:py-24 print:hidden paywall-full-content\" data-test-id=\"post-footer\"\/><\/div>\n<p>#Equillium #Discusses #Mechanistic #Insights #Linking #AhR #Signaling #miR124 #Inflammatory #Disease #Transcript<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Follow Play Earnings CallPlay Earnings Call Equillium, Inc. (EQ) Discusses Mechanistic Insights Linking AhR Signaling and miR-124 in Inflammatory Disease May 27, 2026 11:00 AM EDT Company Participants Stephen Connelly&hellip; <\/p>\n","protected":false},"author":1,"featured_media":656,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[242],"tags":[7671,1587,4025,7668,7674,287,7670,7669,7673,7672,535],"class_list":["post-5211","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-editors-pick","tag-ahr","tag-discusses","tag-disease","tag-equillium","tag-inflammatory","tag-insights","tag-linking","tag-mechanistic","tag-mir124","tag-signaling","tag-transcript"],"_links":{"self":[{"href":"https:\/\/www.fintechpulse8.com\/index.php?rest_route=\/wp\/v2\/posts\/5211","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.fintechpulse8.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.fintechpulse8.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.fintechpulse8.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.fintechpulse8.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=5211"}],"version-history":[{"count":0,"href":"https:\/\/www.fintechpulse8.com\/index.php?rest_route=\/wp\/v2\/posts\/5211\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.fintechpulse8.com\/index.php?rest_route=\/wp\/v2\/media\/656"}],"wp:attachment":[{"href":"https:\/\/www.fintechpulse8.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=5211"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.fintechpulse8.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=5211"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.fintechpulse8.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=5211"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}